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VSMC proliferation and intimal thickening also predispose individuals to oscillatory or low blood flow, which have been shown to induce leukocyte adhesion, enhanced vascular permeability, LDL oxidation, and atherosclerotic plaque formation 42,43,44

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Once outside the cell, GSH degradation occurs exclusively in the extracellular space and only on the surface of cells that express the ectoenzyme -glutamyl transferase

(1)-(5), are as specified in Table 3
