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Analysis of GSH/GSSG after derivatization with N-ethylmaleimide

Abbreviations MSM: methyl sulphonyl methane Vit C: vitamin C GPx: glutathione peroxidise GST: glutathione transferase GR: glutathione reductase HO: heme oxygenase ROS: reactive oxygen species RNS: reactive nitrogen species NO: nitric oxide CO: carbon monoxide GSH: glutathione

By limiting the transport of these molecules to the cell membrane, H 2 decreases NADPH oxidase activity, reduces the generation of ROS, and ultimately achieves an antioxidant effect

However, the exploration of these techniques in models other than cancer still remains in its infancy