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Notably, vasorelaxation was abolished entirely when PI3K or NO synthase inhibitors were applied, confirming the critical role of this pathway (Masodsai et al., 2019)

GSH acts as a direct scavenger of ROS and RNS and as a cofactor for GPx, which catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively
It is essential to note that potential uses of this topical cream are patient-specific and results may vary

Compos Sci Technol 70(1):116122 Devanesan S, AlSalhi MS (2021) Green synthesis of silver nanoparticles using the flower extract of Abelmoschus esculentus for cytotoxicity and antimicrobial studies
