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I have been unwell now for six weeks after the first dose of the Pfizer vaccine

In a study of two patients with refractory lupus who received daratumumab, both patients showed a decrease in disease activity, with downregulation of gene transcripts associated with Tcell activation

As part of this initiative, our team had the opportunity to support the study comprehensively across its full lifecyclereinforcing the value of rigorous late-phase research in real-world clinical environments

Future challenges are also discussed, including the identification of additional missing genetic causes of SLOCA, especially via the use of long-read genome sequencing, improvements in SLOCA prognostication and the implementation of clinical trials of neuroprotective interventions