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[DOI] [PubMed] [Google Scholar] Fasano A
It was found that Mdivi-1 pre-treatment decreased the expression of proteins such as PINK1 and Parkin and diminished cell activity, which was consistent with previous data in IPEC-J2 cells [62]
Seven of the 19 XChem hits were shown to bind to the protein, but with only a modest average peak intensity reduction of 2037% in the CPMG assay (Supplementary Table 2), suggesting that the fragments likely bound with weak (millimolar) affinities, at the very limit of the CPMG assay sensitivity
J Natl Cancer Inst 106:431
