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Ferroptosis as a new therapeutic opportunity for nonviral liver disease

Bent AH, Parseghian C, Morris VK, Kee BK, Huey RW, Morelli MP, Shen JP, Jernigan K, Fernandez A, Harrison C, Horodecky K, Dasari A, Alfaro K, Aziz K, Kell RJ, Kopetz S

Metallothionein and Ceruloplasmin Metallothionein is a protein that binds to metals such as copper and zinc, playing a crucial role in their regulation in the body

The above procedure was repeated with inhibitor concentrations spanning 0.3 60 M to determine the effective concentration (EC 50 ) required to inhibit 50% NNMT activity in cultured adipocytes
