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PLoS One 2014;9:e103379

PDRN works through the A2A adenosine receptor and the nucleotide salvage pathway, supporting cell proliferation and tissue repair

It has been the subject of over 100 peer-reviewed preclinical studies examining its potential roles in tissue repair, gut healing, tendon and ligament recovery, and neuroprotection

Patients typically report fluctuating, widespread dull or aching pain, which may also include neuropathic characteristics such as burning or tingling
