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For a general review on parasite TrxR variants, as well as human TrxR selenoproteins, and the possibility of targeting these for treatment of disease, see Thioredoxin reductase selenoproteins from different organisms as potential drug targets for treatment of human diseases
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doi: 10.1155/2014/467452
The results of this study encourage the use of GlyNAC in patients with HIV to prevent defects related to GSH deficiency
