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When administered in a fixed 1:1 ratio based on ED 50 equivalence, the pregabalinthioctic acid combination (0.151.2 mg/kg + 3.628.8 mg/kg, respectively) yielded intermediate efficacy, with the 1.2 + 28.8 mg/kg dose producing the most sustained threshold elevation (Figure 1C)

Neurosci Let 209 : 201203 Acknowledgements This research was supported by a grant from the University of Siena (PAR 2000)

Myocardial microvascular inflammatory endothelial activation in heart failure with preserved ejection fraction

Mental impairment in aging: selection of patients, methods of evaluation and therapeutic possibilities of acetyl-L-carnitine