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Blood-brain barrier transport, plasma pharmacokinetics, and neuropathology following chronic treatment of the rhesus monkey with a brain penetrating humanized monoclonal antibody against the human transferrin receptor

Wang L, Azad N, Kongkaneramit L, Chen F, Lu Y, Jiang BH, Rojanasakul Y (2008) The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation

In contrast, the activation of the HIF pathway supports the release of cytokines, enhancing NK cellmediated antibacterial defenses, including direct cytotoxicity, but may delay wound closure

For selection of positive transformants 0.1 mg/ml pyrithiamine (Sigma), 0.2 mg/ml hygromycin (Sigma) or 0.02 mg/ml phleomycin (Eubio) was used