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Therefore, the System Xc GSHGPX4 axis constitutes a complete and finely tuned antioxidant defense chain ( via genetic knockout in various cell types, or directly targeting its active site with small molecule inhibitors like RSL3, consistently and efficiently induces typical ferroptosis (Wang L

Blaszkewicz M, Muoz K, Degen GH (2013) Methods for analysis of citrinin in human blood and urine

Alcohol impairs intestinal epithelial cell permeability in vitro through a mechanism mediated by OS (87), supporting therefore the idea that OS may be the main cause of alcohol-induced intestinal leakage (88, 89)

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