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This damage includes DNA strand breaks, which disrupt the expression of essential genes such as proto-oncogenes, oncogenes, and genes involved in DNA repair, thus facilitating tumorigenesis [89,90]

The non-24-hour sleep-wake rhythm disorder is most commonly seen in blindness, since the light-dark cycle is the most powerful cue for synchronizing the hypothalamic pacemaker to the 24-hour day (103)

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Absorption Challenges: Pernicious Anemia and Dietary Factors While some individuals may experience B12 deficiency due to dietary choices, others face challenges in absorbing the vitamin