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Funding This work was supported by the National Natural Science Foundation of China (Grant number: 82270892), the Guidance Project of Scientific Research Program of Hubei Provincial Department of Education (B2019153), the Hubei Provincial Department of Education (Grant Number: Q20202803), the Doctoral Foundation of HuBei University of Science and Technology (Grant Number: BK202011), the Diabetes Open Fund of Hubei University of Science and Technology (Grant Number: 2020TNB17)

Miller R, Buehner G, Chang Y, Harper JM, Sigler R, Smith-Wheelock : Methionine deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-1 and insulin levels and increases hepatocyte MIF levels and stress resistence

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Kim S, Song J, Ernst P, Latimer MN, Ha CM, Goh KY, et al