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For 24-week extended protocol (200mg total): Ten 20mg vials
This creates unpredictable results, inconsistent appetite suppression, and a timeline that does not match what the research suggests
A strong increase in NK cell degranulation has been observed without target MM cells, indicating that Daratumumab may induce NK cell apoptosis by NK cell fratricide or NK-mediated cytotoxicity by ADCC [5, 92]
Addressing these challenges will require interdisciplinary approaches and sustained efforts to optimize the properties of NDBs and streamline their development pipeline for clinical use (Kong et al., 2023)
