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But if you come back every week for a month or so you'll notice a big difference in your overall level of energy." So the very first time someone gets a B12 shot they probably won't feel much of an effect, even though they might experience a bit of an energy boost after the very first one, but it usually only lasts for about a week

Vitamin B12 Regulates Cytokines and Neurotrophic Factors A very new research field has brought to light astonishing new functions of B12 in the nervous system, which go far beyond its role as coenzyme and rather resemble the mode of action of a hormone: vitamin B12 regulates the level of certain neurotrophic factors such as neurotransmitters, growth factors and the so-called cytokines essential messenger substances that all assume a controlling function in numerous bodily processes (32)

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From increased energy and mental clarity to improved nerve function and mood, the benefits are profound and far-reaching