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Mild signs of hypersensitivity: itching or rash

PLoS One 6:e23148

Consistent with the 2018 ISSN position stand on research and recommendations [12], the primary writing team classified dietary antioxidants across both the performance and antioxidant domains using the following evidence-based criteria: (1) High Strong evidence to support efficacy and apparently safe : Supplements backed by solid theory and supported by most well-controlled studies in relevant populations, using proper dosing regimens, demonstrating both effectiveness and safety

Mitochondria are the main source of intracellular ROS, in which the superoxide produced by the electron leakage of the electron transport chain (ETC) produces hydroxyl radicals through a series of reactions, thus driving PUFA-PL peroxidation