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KPV is recognized for its ability to reduce inflammation and support the immune system by inhibiting the activation of NF-kappaB and MAP kinase inflammatory pathways and decreasing proinflammatory cytokine secretion

Effects of oral glutathione supplementation on systemic oxidative stress biomarkers in human volunteers. Journal of Alternative and Complementary Medicine

NRF2 is subsequently stabilized to transcriptionally upregulate antioxidant response genes including xCT, the rate-limiting enzyme in glutathione synthesis, glutamate cysteine ligase (GCL), and enzymes used in detoxification of ROS, such as GPx [42], to attenuate ROS damage

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