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Inhibition of ACSL4 alleviates parkinsonism phenotypes by reduction of lipid reactive oxygen species

[DOI] [PubMed] [Google Scholar] 133.Schisterman E.F., Mumford S.L., Sjaarda L.A

Safety profiles vary significantly : IV administration carries serious risks including anaphylaxis, hepatotoxicity, and potential endotoxin contamination, while oral supplements typically cause only mild gastrointestinal effects like flatulence or loose stools

As we have noted earlier, toxicity may also occur in the liver and occasionally in neural tissue, presumably as a consequence of the widespread tissue occurrence of cysteine S -conjugate -lyases