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Advances in Clinical Chemistry

Although the APF peptide was found in moderately higher abundance in IC/BPS relative to control urine, our results show that the APF peptide was inconsistently present in urine, suggesting that its utility as a sole biomarker of IC/BPS may be limited

That legal status reflects cosmetic regulation, not a therapeutic endorsement

Hydrophobic or charged hydrophilic molecules diffuse poorly through mucus, while uncharged hydrophilic molecules can move quickly through the mucin mesh, with smaller molecules moving almost as fast as water
