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Feature importance was computed using rangers permutation variable importance approach 108 , and then starting with the least important, each input feature was set to the mean value from the training dataset for that feature and the AUC score or Spearman rho coefficient was computed for the testing set and the ZOE PREDICT1 dataset

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[DOI] [PMC free article] [PubMed] [Google Scholar] Lagace TA, Curtis DE, Garuti R, McNutt MC, Park SW, Prather HB, Anderson NN, Ho YK, Hammer RE, Horton JD, 2006