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4 Discussion SLIM1 is an ethylene insensitive 3-like (EIL) family TF that plays an important role in the transcriptional response to S (Maruyama-Nakashita et al., 2006

You wouldn't perform surgery on a dirty table, and you shouldn't reconstitute a sensitive biological compound without the right gear

doi: 10.1056/nejm196803282781306 30
In addition, they may be closer mimetics of a natural -turn with some flexibility which may be important for the effective interactions between a mimetic and a target protein, especially in the induced fit scenario