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10 Conclusion and future perspectives MSCs have emerged as the most promising cellular therapeutic candidates for IVDD due to their distinctive advantages

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Ann Oncol 23(7):17711780 Bayraktar S, Hernadez-Aya LF, Lei X, Meric-Bernstam F, Litton JK, Hsu L, Hortobagyi GN, Gonzalez-Angulo AM (2012) Effect of metformin on survival outcomes in diabetic patients with triple receptor-negative breast cancer

Zinc supplementation in zinc-deficient elderly individuals, such as those in nursing homes, has been shown to improve immune function by enhancing anti-CD3/CD28 and PHA-stimulated T cell proliferation, as well as increasing the number of peripheral T cells [303]