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As Kannt & Pfenninger highlight in Frontiers in Physiology , maintaining NAD levels is a cornerstone of metabolic health, supporting mitochondrial function and improving resistance to metabolic stress (Kannt & Pfenninger, Frontiers in Physiology )

drafted the Introduction, Molecular Pathways, and Conclusion sections, prepared Figure 1, and integrated all sections of the manuscript

Dietary salt restriction and potassium supplementation may be necessary

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