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Studies have demonstrated that carotenoids, particularly -carotene, lutein, and lycopene, showcase vital antioxidant capacity in vivo through quenching singlet oxygen (1O2) and other reactive oxygen species (ROS) by physical and chemical reactions (Young and Lowe, 2018), ( To be specific, carotenoids can efficiently neutralize parlous free radicals by physical quenching of singlet oxygen (1O2) and other ROS, which is importaant for protecting the integrity of cell membranes and organelle functions, particularly under conditions of oxidative stress (Machlin, 2019)

Interestingly, all patients with severe COVID-19 disease and high mortality risk have low basal GSH levels (Khanfar and Al Qaroot, 2020) that could explain an ominous outcome

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