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The PI(3)P hypothesis originated from research on oomycetes, where virulence effectors containing an RxLR motif are directed into plant host cells by binding to PI(3)P on the cell surface followed by endocytosis 39,56 , although this has now been challenged (reviewed in ref
doi: 10.1378/chest.12-2664

Therefore, there is a need for alternate drugs with greater acceptance and fewer side effects

Effects of N-acetylcysteine on semen parameters and oxidative/antioxidant status