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Dosing protocols are individualized based on the patient's condition, body weight, and treatment goals

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Soleimannejad and colleagues reported that black cumin seed extract at 10 and 20 mg/kg improved global ischemia outcomes by a mechanism that involved an increase in gene expression of vascular endothelial growth factor (VEGF), hypoxia-inducible factor-1 (HIF), and matrix metallopeptidase (MMP9) [60]