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For all conditions combined, the most frequently reported benefits include a reported improvement in disease symptoms (45.5%), improved sense of well-being (28.8%), decreased frequency of sinus infections (27.3%), and improved energy (24.2%)

Adzovic L, Lynn AE, DAngelo HM, Crockett AM, Kaercher RM, Royer SE, et al

Importantly, fisetin has been identified as a senolytic agent capable of eliminating senescent cells and attenuating the senescence-associated secretory phenotype (SASP), thereby improving tissue function in preclinical models of aging and chronic disease [22,23]

Cultures were maintained for 25 weeks at 5% CO 2 in 5% FBS, 5% FCS in MEM