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In melanoma, a study utilized endogenous copper ions and click chemistry cascade reactions to successfully amplify the cuproptosis effect, effectively inhibiting tumor growth (Liu et al., 2025)
Moreover, some experiments based on animal models have revealed that Se deficiency has proved the down gradation of lowdensity lipoprotein (LDL) receptor, which is essential for regulating plasma cholesterol levels [111]
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Arch Biochem Biophys 318:231240
