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doi: 10.1016/j.expneurol.2006.12.004

In lupus-prone females, reduced abundance of Erysipelotrichaceae and Bifidobacterium, with increased Lachnospiraceae and Bacteroidetes S247 abundance, has also been reported ( These findings suggest that microbiological dysbioses specific to sex, more precisely the increased prevalence of Lachnospiraceae in females, may account for the earlier onset and greater severity of lupus symptoms

(PubMed) He K, Liu K, Daviglus ML, et al

146 Hypoglossal nerve stimulation may be helpful for individuals with obstructive sleep apnea who fail to respond to CPAP, and greater improvements in AHI can be expected for those with more severe disease, older age, and lower BMI