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and (ii) delivery-related issues, as PLGA nanoparticles require further engineering to achieve high selectivity and specificity, overcome BBB restrictions, and effectively target pathological sites, and/or multi-targeting strategies may be necessary as AD exhibits multiple pathological targets (Lu et al., 2023)
Cell Rep 2017 Jan 17;18(3):659-672 31
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Pharmacologic approaches to glycemic treatment: standards of care in diabetes-2025
