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Drugs 81 (14), 16711675
doi: 10.1016/j.exphem.2024.104153, 58
Asai and coworkers utilized heterologous expression to build unnatural biosynthetic pathways that produce decalin-containing diterpenoid pyrones
Under normal conditions, NNMT activity can consume substantial amounts of both nicotinamide and SAM, particularly in metabolically active tissues or during periods of metabolic stress
