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Recinella L, Orlando G, Ferrante C, Chiavaroli A, Brunetti L, Leone S (2020) Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and Cardiovascular Diseases

However, safety depends on several factors: injection site rotation to avoid lipodystrophy, adequate hydration (both agents can increase fluid demand), and monitoring of B vitamin status since semaglutide may affect nutrient absorption slightly during rapid weight loss phases

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