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Part of the reason for the early disregard for necrotic cell death was probably due to the fact that in contrast to apoptosis, necrosis was considered to be an unregulated form of cell death, which occurred once cellular integrity was compromised due to a multitude of insults

Current research reveals several critical limitations: insufficient investigation into the material basis of Mongolian drugs, a lack of systematic pharmacological studies, unclear pharmacokinetic properties, ambiguous compatibility principles in formulation, and slow progress in the development of new Mongolian medicines (Song et al., 2021)

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Biological samples preparation 50 L of plasma was diluted with 150 L of 0.2 mol/L phosphate buffer, pH 7.8, and treated with 5 L of mixture of 0.1 mol/L BCPB and 0.125 mol/L TCEP for 15 min