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In another trial, a combination of extracts from irvingia and Cissus quadrangularis , a West African vine, produced significantly larger reductions in body weight and fat, total cholesterol, LDL cholesterol, and fasting blood glucose compared with the Cissus extract alone (Oben, Ngondi, Momo 2008)

For women with stress-related amenorrhea or stress-related hypoactive sexual desire disorder, this translates to less irregularity in GnRH pulse frequency and amplitude