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Inflammation Control KPVs anti-inflammatory and antimicrobial effects help calm systemic and local inflammation, supporting smoother healing

Clinically, myocardial injury is indicated by elevated serum biomarkers such as cardiac troponins (cTnI and cTnT) and creatine kinase-MB (CK-MB), and manifests as arrhythmias, reduced ejection fraction, and structural remodeling [106]

418 Mitochondrial dynamics extend beyond internal cellular processes, with CAFs capable of directly transferring functional mitochondria to cancer cells via tunnel nanotubes, enhancing cancer cell bioenergetics and drug resistance

The previous studies report that administration of sitagliptin increases the C-peptide in serum which is essential for the synthesis of insulin, the current study shows that combination therapy has the potential to restore C-peptide