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Michalopoulos, 2010)

The growth and maintenance of BBB are controlled by the interaction between non-cellular elements and endothelial cells [9]

This doesnt mean IF never worksit means it needs to be implemented carefully, often with hormone support, and discontinued if its making sleep or energy worse

New York, NY, March 25, 2016 (1) The Role of the Microbiome in Brain Health and Disease
