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Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of Guinea-pig submucosal neurons

Following FOXO4 displacement, the released p53 undergoes nuclear export and mitochondrial translocation, activating the intrinsic apoptosis pathway via BAX upregulation and BCL-2 downregulation, culminating in caspase-3 cleavage and apoptotic cell death

Erythropoiesis-stimulating agents (ESAs) are widely used to treat anaemia in patients with kidney disease

Lyophilized peptides arrive at the laboratory as a stable, freeze-dried powder, but before they can be used in any experimental protocol, researchers must reconstitute them into solution