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Histamine H Receptor Antagonist (H 2 RA)/Proton Pump Inhibitor (PPI) Induced Vitamin B 12 Depletion Literature suggests that drugs which suppress stomach acid production such as PPIs 159163 and HRAs 164167 interfere with vitamin B 12 absorption, by reducing dietary B12 release from food proteins

It supports mitochondrial function, the bodys powerhouse, helping to break down carbohydrates and fats efficiently

Any disruption along this pathway can lead to deficiency regardless of dietary intake, which is why some patients need supplementation even when they eat B12-rich foods

Therefore, timely intervention and proper treatment are crucial in addressing B12 deficiencies and maintaining overall bodily health