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Additionally, the accumulation of HO-1 metabolites, such as carbon monoxide and biliverdin, in the alveolar microenvironment may further influence the inflammatory and oxidative stress status associated with IPF

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Clinical documentation in the medical record carries the audit trail Per-encounter notes link back to consent, clinical rationale, adverse-event context, and outcomes over time

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Hepatic 25-hydroxylation via cytochrome P450 isoform CYP2R1 converts cholecalciferol to 25(OH)D, followed by renal 1-hydroxylation through CYP27B1 to yield bioactive 1,25(OH)2D [153]

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2.2.1 Curcuma longa L

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