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Several studies have reported that postprandial GLP-1 secretory response from a meal to be significantly diminished in people with T2DM [55, 56]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Jackson T.S., Xu A., Vita J.A., Keaney J.F

We hypothesize that this mutation could promote a more stable interaction of KEAP1 with Cul3, increasing NRF2 degradation and explaining the lower levels in this cell line
