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Peroxynitrite is also involved in the pathogenesis of acute kidney injury induced by sepsis [61], I/R kidney injury [62], diabetic glomerular lesions [63], and lipopolysaccharide-induced renal dysfunction [64]
Finally, in vitro work has looked at cellular signaling downstream of 3-AR engagement, providing mechanistic support for the lipolysis-without-hyperglycemia profile that investigators consistently observe
