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201,202 In an animal model of UC, fecal microbiota transplantation (FMT) significantly improved the diversity of the intestinal microbiota, changed the composition of the intestinal microbiota, and played a role in UC treatment by inhibiting inflammatory factors and protecting the intestinal barrier

Tissue- or phenotype-specific genome scale models can be derived from the general model with recent examples of cancer genome scale models provided by Pacheco et al., [175]

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