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In mammals under no stress conditions, RIDD remains active and can serve a cytoprotective role and this is termed basal RIDD (Dejeans et al

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So, either GFP or SNAP tags are good choices to tag a protein with for visualization

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Nat Rev Mol Cell Biol 24:273287 Dimitrova LN, Kuroha K, Tatematsu T, Inada T (2009) Nascent peptide-dependent translation arrest leads to Not4p-mediated protein degradation by the proteasome

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