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Moreover, TNF- leads to increased synovial levels of Dickkopf-related protein 1 (DKK-1), an inhibitor of osteoblastogenesis [34]

doi: 10.1016/j.surg.2023.09.019 120 AshryRMustafaA-HHausmannKLinnebacherMStrandSSipplWet al

Additionally, BPC 157 is present in most tissues (Seiwerth et al., 2018), where it can bind reactive free radicals and inactivate them at crucial positions not reachable by other antioxidants (Sikiric et al., 1993

doi: 10.1073/pnas.1804938115