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methotrexate glutathione supplementation Synthesis of glutathione-responsive, amphiphilic methotrexate-based prodrug nanoparticles: In vitro and in vivo assessment against metastatic breast cancer Mitochondrial dysfunction and oxidative stress

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Gutsaeva, D

methotrexate glutathione supplementation Synthesis of glutathione-responsive, amphiphilic methotrexate-based prodrug nanoparticles: In vitro and in vivo assessment against metastatic breast cancer Mitochondrial dysfunction and oxidative stress

doi: 10.1016/S0165-0327(00)00199-3 120 SarandolASarandolEEkerSSKaraagacEUHizliBZDiricanMet al

methotrexate glutathione supplementation Synthesis of glutathione-responsive, amphiphilic methotrexate-based prodrug nanoparticles: In vitro and in vivo assessment against metastatic breast cancer Mitochondrial dysfunction and oxidative stress

For the optic nerve crush rat models, the RGC shows a reduction of GPX4 and SLC7A11 expression, increased membrane density, reduced mitochondrial cristae, and increased lipid peroxide and iron levels, indicating RGC ferroptosis after optic nerve crush (Guo et al., 2022)

methotrexate glutathione supplementation Synthesis of glutathione-responsive, amphiphilic methotrexate-based prodrug nanoparticles: In vitro and in vivo assessment against metastatic breast cancer Mitochondrial dysfunction and oxidative stress

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methotrexate glutathione supplementation Synthesis of glutathione-responsive, amphiphilic methotrexate-based prodrug nanoparticles: In vitro and in vivo assessment against metastatic breast cancer Mitochondrial dysfunction and oxidative stress

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