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Of all the substances, treatment with compounds 28 and 28d was the most successful in returning the biochemical mediators to their most normal state and significantly reduced the reactive oxygen and nitrogen species linked to the neuroinflammation mechanism (Table 1)

[DOI] [PubMed] [Google Scholar] 84.Koistinaho J., Miettinen S., Keinnen R., Vartiainen N., Roivainen R., Laitinen J.T

However, the efficacy of nasal absorption may vary among research subjects, and it may not be as potent as the injectable route

[ [PMID: 23055641]
