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The nasal spray format presents the active compound in a pre-constituted aqueous solution, providing a standardised intranasal delivery vehicle for experimental mucosal absorption and bioavailability research

This is because acute surges in blood glucose and insulin that follow meals (postprandial period) are important contributors to the overall adverse effects caused by excessive glucose and insulin levels

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These sharp crystals can physically sever the delicate cyclic structure of the peptide, leading to significant compound degradation