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As a consequence of cell death, its intracellular components are released as pro-inflammatory damage-associated molecular patterns (DAMPs) such as ATP, nucleotides, histones, and high-mobility group protein B1 (HMGB1) and pro-inflammatory cytokines, such as interleukin1 (IL1), IL33, and interferon (IFN) upon plasma membrane rupture, which triggers the innate immune system [48]

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In fact, AD patients might benefit from the consumption of SIRT1 activators but should avoid the intake of SIRT1 inhibitors

9,10-DPA is a material used in organic light-emitting diodes and can also serve as an electron transfer reagent for electron transfer dissociation reactions