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Additionally, the vascular endothelium (the inner lining of the blood vessels) requires significant energy to produce nitric oxide, a molecule essential for regulating blood vessel dilation and constriction

22 Additionally, CBT addresses the psychological aspects of chronic pain, helping patients to cope with and manage pain, thereby enhancing treatment outcomes when combined with pharmacotherapy (Fig

[Epub ahead of print] [DOI] [PubMed] [Google Scholar] 106.Kurppa K, Ashorn M, Iltanen S, Koskinen LL, Saavalainen P, Koskinen O, Maki M, Kaukinen K

In the context of hepatic IR associated with non-alcoholic fatty liver disease (NAFLD), this molecular pathway becomes dysregulated, leading to impaired suppression of hepatic gluconeogenesis