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Front Immunol 5:521

These findings indicate that it could be a promising treatment for a common condition known as delayed gastric emptying

GlpBio Products Cited In Reputable Papers Description of Ipamorelin (acetate) Ipamorelin is a pentapeptide growth hormone secretagogue (GHS) and GHS receptor 1a (GHS-R1a) agonist.1,2 It binds to COS-7 cells expressing GHS-R1a (Ki = 63.4 nM), induces inositol-1,4,5-triphosphate (IP3) accumulation in BHK cells expressing GHS-R1a (EC50 = 46.9 nM), and induces GH release in primary rat pituitary cells (EC50 = 1.3 nM).1 Ipamorelin increases plasma levels of GH in rats and pigs (ED50s = 80 and 2.3 nmol/kg, respectively) but does not increase plasma levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin, or thyroid stimulating hormone (TSH) in pigs when administered at a dose of 420 nmol/kg.2 It increases gastric emptying in a rat model of postoperative ileus induced by laparotomy and intestinal manipulation when administered at doses of 0.014 or 0.14 mol/kg.3 Ipamorelin (18-450 g/animal) increases body weight and longitudinal bone growth in rats.4 Chemical Properties of Ipamorelin (acetate) Complete Stock Solution Preparation Table of Ipamorelin (acetate) Molarity Calculator Dilution Calculator Molecular Weight Calculator Calculate In vivo Formulation Calculator (Clear solution) of Ipamorelin (acetate) Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment) mg/kg g L Step 2: Enter the in vivo formulation (This is only the calculator, not formulation

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